299537
Trifluoroacetic acid
≥99%, for protein sequencing
동의어(들):
TFA
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
CF3COOH
CAS 번호:
Molecular Weight:
114.02
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-929-3
Beilstein/REAXYS Number:
742035
MDL number:
Assay:
≥99%
Form:
liquid
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
SMILES string
OC(C(F)(F)F)=O
vapor density
3.9 (vs air)
vapor pressure
97.5 mmHg ( 20 °C)
type
for protein sequencing
assay
≥99%
form
liquid
impurities
<0.05% water
evapn. residue
<0.005%
refractive index
n20/D 1.3 (lit.)
pH
1 (20 °C, 10 g/L)
Quality Level
mp
−15.4 °C (lit.)
solubility
water: soluble 10.000 g/L
density
1.489 g/mL at 20 °C (lit.)
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General description
Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination.
- High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues.
- Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR.
- Ensures Integrity of Genetic Material: Promotes reliable and reproducible results.
- Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency.
Trifluoroacetic acid is a naturally occurring organic solvent and biodegradable by microbial action. It can also be used as a catalyst for various organic transformations, including solvolysis, rearrangements, reductions, oxidations, and trifluoromethylation.
Application
Trifluoroacetic acid can be used as a solvent in the:
- Mass spectrometry for protein identification.
- Microwave-irradiated bromination of isoxazoles and pyrazoles with N-bromosuccinimide to synthesize mono-brominated isoxazoles and pyrazoles.
- Lewis acid-catalyzed 6-endo-digcyclization of 2-(2-arylethynyl)heteroaryl esters to heterocyclic lactones.
- Electrospinning of cellulose acetate to prepare the corresponding nanofibrous membranes.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
저장 등급
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
No data available
flash_point_c
No data available
Andrew C Tolonen et al.
Journal of visualized experiments : JoVE, (89)(89), doi:10-doi:10 (2014-07-22)
Stable isotope labeling of peptides by reductive dimethylation (ReDi labeling) is a method to accurately quantify protein expression differences between samples using mass spectrometry. ReDi labeling is performed using either regular (light) or deuterated (heavy) forms of formaldehyde and sodium
Guangfa Shi et al.
Organic letters, 17(1), 38-41 (2014-12-18)
Direct trifluoromethylation of arenes using TFA as the trifluoromethylating reagent was achieved with Ag as the catalyst. This reaction not only provides a new protocol for aryl C-H trifluoromethylation, but the generation of CF3· from TFA may prove useful in
W C Mahoney et al.
The Journal of biological chemistry, 255(23), 11199-11203 (1980-12-10)
A method employing reverse phase high performance liquid chromatography has been developed for the purification of large denatured peptides. The cyanogen bromide fragments of hemoglobin alpha, beta, and gamma chains (13 to 91 residues in length) could be separated and
Continuous-flow synthesis of the anti-malaria drug artemisinin.
François Lévesque et al.
Angewandte Chemie (International ed. in English), 51(7), 1706-1709 (2012-01-18)
Risto Kostiainen et al.
Journal of chromatography. A, 1216(4), 685-699 (2008-09-19)
The most widely used ionization techniques in liquid chromatography-mass spectrometry (LC-MS) are electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI). All three provide user friendly coupling of LC to MS. Achieving optimal LC-MS conditions is
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