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Merck

G8644

D-(+)-Glucose solution

100 g/L in H2O, sterile-filtered, BioXtra, suitable for cell culture

동의어(들):

D-Glucopyranose

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C6H12O6
CAS 번호:
Molecular Weight:
180.16
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.75
Beilstein/REAXYS Number:
1281608
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SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

sterility

sterile-filtered

product line

BioXtra

form

solution

concentration

100 g/L in H2O

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

storage temp.

room temp

Quality Level

Gene Information

human ... PYGM(5837)

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General description

Glucose provides the primary energy source for cell metabolism. It is a main source of energy for living organisms. Glucose occurs naturally in the free state in fruits and other parts of plants. It is combined into glucosides, disaccharides, oligosaccharides, the polysaccharides (cellulose and starch), and glycogen.

Application

D-(+)-Glucose solution has been used:

  • to determine extracellular acidification rate (ECAR) or oxygen consumption rate (OCR) in human CB CD34+cells by Seahorse extracellular flux assay
  • as a negative control in human umbilical vein endothelial cell (HUVEC) culture
  • as a supplement for culturing colonic biopsies

Biochem/physiol Actions

Glucose is an aldosic monosaccharide and acts as an important component of glycolysis and downstream pathways for aerobic and anaerobic respiration. It provides energy for growth and reproduction. Glucose is a byproduct of photosynthesis that is condensed to starch in plants and cyanobacteria.

Other Notes

This product has been tested with cell lines to verify the product is not cytotoxic. The growth promoting capacity of this cell culture tested glucose solution was assessed at 45 mL/L in medium using appropriate cell lines.
This solution has been sterilized by filtration.

저장 등급

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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시험 성적서(COA)

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문서 라이브러리 방문

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Physiological genomics, 46(8), 302-308 (2014-02-20)
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Dieter Henrik Heiland et al.
Nature communications, 10(1), 2541-2541 (2019-06-13)
Reactive astrocytes evolve after brain injury, inflammatory and degenerative diseases, whereby they undergo transcriptomic re-programming. In malignant brain tumors, their function and crosstalk to other components of the environment is poorly understood. Here we report a distinct transcriptional phenotype of
Andreia V Pinho et al.
PloS one, 10(6), e0128012-e0128012 (2015-06-06)
Sirtuin 1 (Sirt1) has been reported to be a critical positive regulator of glucose-stimulated insulin secretion in pancreatic beta-cells. The effects on islet cells and blood glucose levels when Sirt1 is deleted specifically in the pancreas are still unclear. This
Rawand Masoud et al.
Cell reports. Medicine, 1(8), 100143-100143 (2020-12-10)
Mitochondrial respiration (oxidative phosphorylation, OXPHOS) is an emerging target in currently refractory cancers such as pancreatic ductal adenocarcinoma (PDAC). However, the variability of energetic metabolic adaptations between PDAC patients has not been assessed in functional investigations. In this work, we

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