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205805

Carbenicillin, Disodium Salt

Synthetic penicillin derivative for ampicillin-resistant plasmids. Blocks bacterial cell wall formation. Effective against Gram-negative bacteria.

Synonym(s):

Carbenicillin, Disodium Salt, 6-[(Carboxyphenylacetyl)-amino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic Acid, 2Na

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About This Item

Empirical Formula (Hill Notation):
C17H16N2O6S · 2Na
CAS Number:
4800-94-6
Molecular Weight:
422.36
UNSPSC Code:
51282413
MDL number:
MFCD00077683
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Quality Segment

100

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

light beige

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[Na+].S1[C@H]2N([C@H](C1(C)C)C(=O)[O-])C(=O)[C@H]2NC(=O)C(c3ccccc3)C(=O)[O-]

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

General description

Synthetic penicillin derivative for ampicillin-resistant plasmids. Blocks bacterial cell wall formation. Effective against Gram-negative bacteria.
Synthetic penicillin derivative used for gene technology when carbenicillin-resistant plasmids are studied. Typically used at 30-50 µg/ml for selection of carbenicillin-resistant Escherichia coli.

Biochem/physiol Actions

Potency: ≥770 µg/mg

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions are stable for 72 h at 4°C or for 4 months at -20°C.

Other Notes

Payne, D.J., and Amyes, S.G. 1993. J. Med. Microbiol. 38, 114.
DeSutter, K., et al. 1992. Mol. Microbiol.6, 2201.
Monraie, D., et al. 1992. FEBS Lett.306, 108.
Sakurai, Y., et al. 1991. J. Bacteriol.173, 7038.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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