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102735 L-Cysteine hydrochloride monohydrate

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102735
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #EC NumberHill FormulaMolar MassGrade Value
      7048-04-6200-157-7C₃H₈ClNO₂S * H₂O175.60 g/molPh Eur,JP,USP
      Description
      Catalogue Number102735
      SynonymsCys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate
      References
      Product Information
      CAS number7048-04-6
      EC number200-157-7
      GradePh Eur,JP,USP
      Hill FormulaC₃H₈ClNO₂S * H₂O
      Molar Mass175.60 g/mol
      HS Code2930 90 16
      Structure formula ImageStructure formula Image
      Quality SegmentMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.51 g/cm3
      Melting Point176 °C
      pH value0.8 - 1.2 (100 g/l, H₂O, 20 °C)
      Vapor pressure<0.1 hPa (20 °C)
      Bulk density780 kg/m3
      Solubility650 g/l
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSHA2285000
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (alkalimetric, calculated on dried substance)98.5 - 101.0 %
      Identity (IR-spectrum)passes test
      Identity (specific rotation)passes test
      Identity (wet chemistry)passes test
      Appearancewhite to almost white crystalline powder or colorless crystals
      Appearance of solution (25 g/l, water)clear and not more intense in color than reference solution BY₆
      Appearance of solution (100 g/l, water)clear and colorless
      pH (10 g/l, CO₂-free water)1.3 - 2.3
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+5.5 to +7.0
      Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+5.7 to +6.8
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+6.0 to +7.5
      Sulfate (SO₄)≤ 200 ppm
      Heavy metals (as Pb)≤ 10 ppm
      Fe (Iron)≤ 10 ppm
      Related substances (TLC)passes test
      Related Compounds, total (TLC)≤ 0.5 %
      Ninhydrin-positive substances (LC) (impurity A (570 nm))≤ 0.5 %
      Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
      Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
      Ninhydrin-positive substances (LC) (total impurities)≤ 1.0 %
      Residual solvents (ICH Q3C)excluded by manufacturing proces
      Sulfated ash (600 °C)≤ 0.1 %
      Loss on drying (Vacuum < 2,0 kPa, P2O5, 20 h)8.5 - 12.0 %
      Bacterial endotoxins≤ 6.0 I.U./g
      Microbiological test (total aerobic microbial count (TAMC))≤ 10²
      Microbiological test (total yeast and mould count (TYMC))≤ 10²
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph. Eur., JP, USP.
      Global Trade ITEM Number
      Catalogue Number GTIN
      102735 0

      Documentation

      Material Qualification Dossier

      TitleVersion
      11.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      L-Cysteine hydrochloride monohydrate SDS

      Title

      Safety Data Sheet (SDS) 

      L-Cysteine hydrochloride monohydrate Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      102735 PDF Specification Document

      Certificates

      Title