P4019
Brij® S20
Synonym(s):
Polyethylene glycol octadecyl ether, Polyoxyethylene (20) stearyl ether
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About This Item
Linear Formula:
C18H37(OCH2CH2)nOH, n~20
CAS Number:
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
InChI
1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI key
PSEGVHKUPXNGGJ-UHFFFAOYSA-N
form
solid
mp
44-46 °C (lit.)
HLB
15
Quality Level
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Related Categories
Application
- Nanostructured lipid carriers for oral delivery of silymarin: Improving its absorption and in vivo efficacy in type 2 diabetes and metabolic syndrome model.: This study utilizes Brij® S20 to develop nanostructured lipid carriers for oral delivery of silymarin. The findings demonstrate enhanced absorption and efficacy of silymarin in treating type 2 diabetes and metabolic syndrome, highlighting the potential of Brij® S20 in improving drug delivery systems. (Piazzini et al., 2019).
- Water-stable all-biodegradable microparticles in nanofibers by electrospinning of aqueous dispersions for biotechnical plant protection.: The study uses Brij® S20 to create water-stable, biodegradable microparticles in nanofibers through electrospinning. These microparticles are designed for biotechnical plant protection, demonstrating the potential of Brij® S20 in agricultural biotechnology. (Bansal et al., 2012).
General description
Brij® S20 is a surfactant that belongs to the class of polyoxyethylene ethers. It is majorly used in pharmaceutical applications to improve the solubility of the drugs. It can also be grafted on a variety of surfaces to enhance the intracellular uptake of dyes.
Legal Information
Brij is a registered trademark of Croda International PLC
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Nanostructured lipid carriers as promising delivery systems for plant extracts: The case of silymarin
Piazzini V, et al.
Applied Sciences, 8(7), 1163-1163 (2018)
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations
Xiong W, et al.
Carbohydrate Polymers, 204, 89-96 (2019)
Wei Xiong et al.
International journal of nanomedicine, 13, 3781-3793 (2018-07-11)
Berberine (BBR) is a plant-derived benzylisoquinoline alkaloid and has been demonstrated to be a potential treatment for various chronic diseases. The poor water solubility and P-glycoprotein (Pgp)-mediated drug efflux are the main challenges for its further application in a clinical
S Rahima Benhabbour et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 63-71 (2011-11-01)
Lipid-based oil-filled nanoparticles (NPs) with a high concentration of surface-chelated nickel (Ni-NPs) were successfully prepared using a Brij 78-NTA-Ni conjugate synthesized with Brij 78 (Polyoxyethylene (20) stearyl ether) and nitrilotriacetic acid (NTA). The facile incorporation of the Brij 78-NTA-Ni conjugate
L Realini et al.
Journal of clinical microbiology, 35(11), 2791-2794 (1997-11-14)
We report on the influences of polyoxyethylene stearate (POES), PANTA, and pH on primary cultures of Mycobacterium genavense in BACTEC vials. As a model for primary cultures from tissue, seven different strains first isolated from AIDS patients (five from Switzerland
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