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About This Item
Empirical Formula (Hill Notation):
C17H34NO8P
CAS Number:
Molecular Weight:
411.43
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
06:0 PE, 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (850697P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850697P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
InChI
1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
InChI key
PELYUHWUVHDSSU-OAHLLOKOSA-N
General description
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.
06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Application
06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
- as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
- as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
- as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).
Biochem/physiol Actions
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.
06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Packaging
5 mL Clear Glass Sealed Ampule (850697P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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