8.52112
Fmoc-Lys(Me3Cl)-OH
Novabiochem®
Synonym(s):
Fmoc-Lys(Me₃Cl)-OH, N-α-Fmoc-N-ε-trimethyl-N-L-lysine · chloride
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About This Item
Empirical Formula (Hill Notation):
C24H31ClN2O4
CAS Number:
Molecular Weight:
446.97
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
Quality Segment
product line
Novabiochem®
assay
≥95% (TLC), ≥95.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
SMILES string
Cl.[N+](CCCC[C@H](N=C([O-])OCC1c2c(cccc2)c3c1cccc3)C(=O)O)(C)(C)C
InChI
1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
InChI key
XUJRNPVABVHOAJ-FTBISJDPSA-N
General description
A novel derivative for the introduction of trimethyl-lysine during Fmoc SPPS. Ref [1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS
Literature references
[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS
Literature references
[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
LC/MS: passes test
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
LC/MS: passes test
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 04-12-1270
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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