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8.17072

TWEEN^® 20 (Polysorbate)

Name: TWEEN<SUP>®</SUP> 20 (Polysorbate)
Brand: MM

EMPROVE^® ESSENTIAL, Ph. Eur., JPE, NF

Synonym(s):

TWEEN^® 20, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate

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About This Item

CAS Number:

9005-64-5

UNSPSC Code:

12352104

EC Index Number:

500-018-3

MDL number:

MFCD00165986

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Properties

Quality Segment

500

agency

JPE, NF, Ph. Eur.

vapor pressure

<1.4 hPa ( 20 °C)

product line

EMPROVE^® ESSENTIAL

form

viscous liquid

mol wt

~1228

technique(s)

API processing | nano-milling: suitable

refractive index

n20/D 1.468 (lit.)

pH

6-8 (20 °C, 50 g/L in H₂O)

transition temp

flash point 275 °C

density

1.095 g/mL at 25 °C (lit.)

application(s)

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

15-25°C

SMILES string

CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Non-ionic detergent

Polysorbate 20 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

527.0 °F - Pensky-Martens closed cup

flash_point_c

275 °C - Pensky-Martens closed cup

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Global Trade Item Number

SKU	GTIN
8.17072.2500	04022536685908
8.17072.1000	04022536685885
8.17072.9025	04065272420457