Quality Segment
assay
≥95% (HPLC)
form
buffered aqueous solution
concentration
0.1 mg/mL in 0.1 M sodium acetate pH 5.0
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell membrane | interferes
shipped in
dry ice
storage temp.
−20°C
General description
Chemical structure: peptide
Application
Pediocins have molecular masses of about 2,700 to 4,000 Da. They are potential food biopreservatives used to control food-borne pathogens and spoilage.
Biochem/physiol Actions
Pediocins are class IIa bacteriocins that are produced by Pediococcus acidilactici. They are cationic peptides with molecular masses of about 2,700 to 4,000 Da, that show strong activity against pathogenic bacteria such as Listeria monocytogenes, Clostridicum perfringes, Enterococcus faecalis, and Staphylococcus aureus.4 This antimicrobial action of pediocins is based on interactions with the cytoplasmic membrane, resulting in pore formation and cell death. These interactions also cause a change in membrane potentials, which leads to a loss of the proton motive force and an efflux of intracellular ions, ultimately causing cell death. They have been shown to inhibit Listeria monocytogenes.
Other Notes
50ug
Keep container tightly closed in a dry and well-ventilated place.
저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)