S1885
Suberic acid bis(N-hydroxysuccinimide ester)
≥95%, powder
Synonym(s):
Disuccinimidyl suberate, Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)
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About This Item
Empirical Formula (Hill Notation):
C16H20N2O8
CAS Number:
Molecular Weight:
368.34
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥95%
Form:
powder
Quality Segment
assay
≥95%
form
powder
reaction suitability
reagent type: cross-linking reagent
solubility
chloroform: 50 mg/mL, DMF: soluble, aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)
functional group
imide
storage temp.
2-8°C
SMILES string
O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
InChI
1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2
InChI key
ZWIBGKZDAWNIFC-UHFFFAOYSA-N
General description
Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.
Application
Suberic acid bis(N-hydroxysuccinimide ester) has been:
- supplemented in pierce lysis buffer used for immunoprecipitation
- used to conjugate the oligonucleotide standards to gelatin
- used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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