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About This Item
NACRES:
NA.47
UNSPSC Code:
12352200
Product Name
MILLIPLEX® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A,
species reactivity
nonhuman primates
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
serum
plasma
assay range
accuracy: 80-102%, inter-assay cv: <20%
intra-assay cv: <10%, inter-assay cv: <30%
(TNF-α)
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
Cytokines are small proteins secreted by immune cells that regulate immune responses, hematopoiesis, and lymphocyte development, including interleukins, interferons, and chemokines. Growth factors, which promote cell growth and proliferation, share structural and functional similarities with cytokines and act through specific receptors on target cells. Unlike hormones produced by specialized glands, both cytokines and growth factors can be secreted by various cell types, and their tightly regulated expression is crucial; dysregulation can lead to diseases such as infections, autoimmune disorders, and cancer. Research on these molecules is essential for understanding the immune system and developing therapeutic strategies, with non-human primates serving as important models due to their genetic similarity to humans.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 48 analytes in non-human primate serum, plasma, and cell culture supernatants.
Analytes included: BCA-1, sCD137, CD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1α, MIP-1β, MIP-3α, Perforin, RANTES, TGFα, TNFα, TNFβ, VEGF-A
Note: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: BCA-1, sCD137, CD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1α, MIP-1β, MIP-3α, Perforin, RANTES, TGFα, TNFα, TNFβ, VEGF-A
Note: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Tailored for Non-Human Primate Research: Specifically developed to support studies involving non-human primate samples, ensuring accurate and relevant data for translational and preclinical research.
Space-Saving Bulk Packaging: Reduce cold storage demands with compact bulk premixed kits—perfect for labs with limited freezer or fridge space.
Flexible Incubation Options: Offers both rapid (2 hour) and overnight incubation protocols to suit different workflow needs and sensitivity requirements.
Low Sample Volume Requirement: Requires minimal sample input (25µL), preserving valuable biological material and enabling repeated testing.
Comprehensive Coverage: Largest commercially available multiplex panel specifically designed for NHP research.
Space-Saving Bulk Packaging: Reduce cold storage demands with compact bulk premixed kits—perfect for labs with limited freezer or fridge space.
Flexible Incubation Options: Offers both rapid (2 hour) and overnight incubation protocols to suit different workflow needs and sensitivity requirements.
Low Sample Volume Requirement: Requires minimal sample input (25µL), preserving valuable biological material and enabling repeated testing.
Comprehensive Coverage: Largest commercially available multiplex panel specifically designed for NHP research.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
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