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8.05740

2-Mercaptoethanol

for synthesis

Synonym(s):

Thioethylene glycol, Thioglycol, β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylene glycol

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About This Item

Linear Formula:
HSCH2CH2OH
CAS Number:
60-24-2
Molecular Weight:
78.13
UNSPSC Code:
12352104
NACRES:
NA.22
EC Index Number:
200-464-6
MDL number:
MFCD00004890
Beilstein/REAXYS Number:
773648
Assay:
≥99% (GC)
Form:
liquid
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vapor density

2.69 (vs air)

Quality Segment

200

vapor pressure

1 mmHg ( 20 °C)

assay

≥99% (GC)

form

liquid

autoignition temp.

295 °C

potency

98-162 mg/kg LD50, oral (Rat), 112-224 mg/kg LD50, skin (Rabbit)

expl. lim.

18 %

reaction suitability

reagent type: reductant

concentration

14.3 M (pure liquid)

pH

4.5-6 (20 °C, 500 g/L in H2O)

bp

157 °C (lit.)

mp

<-50 °C

transition temp

flash point 70.5 °C

density

1.114 g/mL at 25 °C (lit.)

storage temp.

2-30°C

SMILES string

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

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Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

target_organs

Liver,Heart

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Poisonous substance

pdsc

Class II Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

8057409025: + 8057409999: + 8057401000: + 8057400005: + 8057400000: + 8057400250:

jan

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