SAB4200721
Anti-GABA antibody, Mouse monoclonal
clone GB-69, purified from hybridoma cell culture
別名:
Mouse Anti-Gamma-aminobutyric acid
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この商品について
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
GB-69, monoclonal
Species reactivity:
rat, monkey, frog, mouse, human, gerbil
Application:
DB, ELISA, IF, IHC
Citations:
3
biological source
mouse
Quality Segment
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
GB-69, monoclonal
form
buffered aqueous solution
species reactivity
rat, monkey, frog, mouse, human, gerbil
concentration
~1.0 mg/mL
technique(s)
ELISA: suitable, dot blot: suitable, immunofluorescence: 5-10 μg/mL using human pancreatic tumor AsPC1 cell line, immunohistochemistry: 1-2.5 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human brain and/or cerebellum sections
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GABRA1(2554)
mouse ... Gabra1(14394)
rat ... Gabra1(29705)
rhesus monkey ... Gabra1(574302)
General description
Anti-GABA antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GB-69 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified GABA conjugated to BSA. γ-Aminobutyric acid (GABA) is present in the central nervous system (CNS) of vertebrates. GABA is formed following enzymatic decarboxylation of L-glutamic acid by glutamic acid decarboxylase (GAD).
Immunogen
purified GABA conjugated to BSA
Application
Anti-GABA antibody, Mouse monoclonal has been used in:
- immunofluorescence
- immunohistochemistry
- enzyme linked immunosorbent assay (ELISA)
- dot-blot
Biochem/physiol Actions
γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter. GABA mediates fast synaptic inhibition in the mature nervous system and plays multiple key roles as sensory circuits undergo functional development. GABA promotes proliferation of immune cells, embryonic stem cells and cortical progenitor cells. In addition, it is involved in protein synthesis and metabolism and plays a major role in the regulation of muscle tone, blood pressure, heart rate and respiration.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable