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437720 Lipoxin A₄ - CAS 89663-86-5 - Calbiochem

Lipoxin A₄, CAS 89663-86-5, is a potent inhibitor of cytotoxic activity of human natural killer cells. Shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides.

Lipoxin A₄ - CAS 89663-86-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LXA₄, 5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-trans-tetraenoic Acid

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437720
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
89663-86-5C₂₀H₃₂O₅

Products

Catalogue NumberPackaging Qty/Pack
437720-25UGCN Glass bottle 25 μg
Description
OverviewPotent inhibitor of cytotoxic activity of human natural killer cells; shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides. Involved in contractile responses and acts as a potent activator of human protein kinase C. Stimulates rapid lipid remodeling and pertussis-sensitive release of arachidonic acid in polymorphonuclear leukocytes. Stimulates MAP kinases via activation of G protein-coupled receptors.
Caution! Product contains volatile liquid. Keep product cold at all times.
Catalogue Number437720
Brand Family Calbiochem®
SynonymsLXA₄, 5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-trans-tetraenoic Acid
References
ReferencesMcMahon, B., et al. 2000. J. Biol. Chem. 275, 27566.
Soyombo, O., et al. 1994. Allergy 49, 230.
Flore, S., et al. 1992. J. Biol. Chem. 267, 16168.
Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 3438.
Product Information
CAS number89663-86-5
ATP CompetitiveN
FormLiquid
FormulationIn Ethanol.
Hill FormulaC₂₀H₃₂O₅
Chemical formulaC₂₀H₃₂O₅
ReversibleN
Structure formula ImageStructure formula Image
Quality SegmentMQ100
Applications
Biological Information
Primary TargetPotent inhibitor of cytotoxic activity of human natural killer cells
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 11-36/37/38

Highly flammable.
Irritating to eyes, respiratory system and skin.
S PhraseS: 16-26-36-7

Keep away from sources of ignition - No Smoking.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Keep container tightly closed.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Flammable
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Catalogue Number GTIN
437720-25UGCN 04055977186888

Documentation

Lipoxin A₄ - CAS 89663-86-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Lipoxin A₄ - CAS 89663-86-5 - Calbiochem Certificates of Analysis

TitleLot Number
437720

References

Reference overview
McMahon, B., et al. 2000. J. Biol. Chem. 275, 27566.
Soyombo, O., et al. 1994. Allergy 49, 230.
Flore, S., et al. 1992. J. Biol. Chem. 267, 16168.
Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 3438.

Brochure

Title
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-August-2008 RFH
SynonymsLXA₄, 5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-trans-tetraenoic Acid
DescriptionPotent inhibitor of cytotoxic activity of human natural killer cells. Shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides. Involved in contractile responses and acts as a potent enhancer of human protein kinase C. Stimulates the rapid lipid remodeling and pertussis-sensitive release of arachidonic acid in polymorphonuclear leukocytes.
FormLiquid
FormulationIn Ethanol.
CAS number89663-86-5
Chemical formulaC₂₀H₃₂O₅
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityEthanol
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Flammable
ReferencesMcMahon, B., et al. 2000. J. Biol. Chem. 275, 27566.
Soyombo, O., et al. 1994. Allergy 49, 230.
Flore, S., et al. 1992. J. Biol. Chem. 267, 16168.
Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 3438.