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580567 TCEP, Hydrochloride, Reagent Grade - CAS 51805-45-9 - Calbiochem

TCEP, Hydrochloride, Reagent Grade - CAS 51805-45-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: tris(2-Carboxyethyl)phosphine, HCl

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Overview

Replacement Information
Description
OverviewA water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 minutes. TCEP is also capable of functioning as a reducing agent even in the pH range of 1.5-8.5. It is more resistant to air-oxidation as compared to DTT.
Catalogue Number580567
Brand Family Calbiochem®
Synonymstris(2-Carboxyethyl)phosphine, HCl
References
ReferencesGetz, E.B., et al. 1999. Anal. Biochem. 273, 73.
Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.
Product Information
CAS number51805-45-9
FormWhite solid
Hill FormulaC₉H₁₅O₆P & BULL; HCl
Chemical formulaC₉H₁₅O₆P & BULL; HCl
Quality SegmentMQ100
Applications
Biological Information
Purity≥98% by GC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 34

Causes burns.
S PhraseS: 26-27-36/37/39

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Take off immediately all contaminated clothing.
Wear suitable protective clothing, gloves and eye/face protection.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Corrosive
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). TCEP retains stability when stored at an acidic or alkaline pH; avoid storage at pH 7.0-8.0. Also avoid exposure to high concentrations of phosphate ions (>150 mM). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Catalogue Number GTIN
580567 0

Documentation

TCEP, Hydrochloride, Reagent Grade - CAS 51805-45-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

TCEP, Hydrochloride, Reagent Grade - CAS 51805-45-9 - Calbiochem Certificates of Analysis

TitleLot Number
580567

References

Reference overview
Getz, E.B., et al. 1999. Anal. Biochem. 273, 73.
Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-September-2022 JSW
Synonymstris(2-Carboxyethyl)phosphine, HCl
DescriptionA water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 minutes. TCEP is also capable of functioning as a reducing agent even in the pH range of 1.5-8.5. It is more resistant to air-oxidation as compared to DTT.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number51805-45-9
Chemical formulaC₉H₁₅O₆P & BULL; HCl
Purity≥98% by GC
SolubilityH₂O (50 mg/ml)
Storage Protect from moisture
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). TCEP retains stability when stored at an acidic or alkaline pH; avoid storage at pH 7.0-8.0. Also avoid exposure to high concentrations of phosphate ions (>150 mM). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Corrosive
ReferencesGetz, E.B., et al. 1999. Anal. Biochem. 273, 73.
Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.