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444244 MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem

The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy

Primary Target: MMP-2
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
10335-69-0C₁₈H₃₅NO₂

Products

Catalogue NumberPackaging Qty/Pack
444244-10MGCN 塑膠安瓿;塑膠針藥瓶 10 mg
Description
OverviewA cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
Catalogue Number444244
Brand Family Calbiochem®
Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
References
ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
Product Information
CAS number10335-69-0
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₈H₃₅NO₂
Chemical formulaC₁₈H₃₅NO₂
ReversibleN
Structure formula ImageStructure formula Image
Quality SegmentMQ100
Applications
Biological Information
Primary TargetMMP-2
Primary Target K<sub>i</sub>1.7 mM
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Catalogue Number GTIN
444244-10MGCN 04055977186468

Documentation

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem Certificates of Analysis

TitleLot Number
444244

References

Reference overview
Berton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.

Citations

Title
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision14-November-2023 JSW
    Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
    DescriptionPotent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)
    FormWhite solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number10335-69-0
    Chemical formulaC₁₈H₃₅NO₂
    Structure formulaStructure formula
    Purity≥98% by HPLC
    SolubilityDMSO (2 mg/ml) or Ethanol (3 mg/ml)
    Storage Protect from light
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsUnstable in solution; reconstitute just prior to use.
    Toxicity Standard Handling
    ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
    Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
    Citation
  • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
  • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
  • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
    		•