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Merck

62476

Lithium chloride

BioUltra, Molecular Biology, anhydrous, ≥99.0% (AT)

Synonym(s):

LiCl

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About This Item

Linear Formula:
LiCl
CAS Number:
Molecular Weight:
42.39
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-212-3
MDL number:
Assay:
≥99.0% (AT)
Grade:
Molecular Biology
Form:
powder or crystals
Solubility:
H2O: 1 M at 20 °C, clear, colorless
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grade

Molecular Biology

Quality Level

product line

BioUltra

assay

≥99.0% (AT)

form

powder or crystals

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected, ≤0.001% total nitrogen (N)

loss

≤1% loss on drying, 110 °C

pH

5.0-7.5 (25 °C, 1 M in H2O)

mp

605 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.2 mg/kg, Ba: ≤10 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤10 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.01, λ: 280 nm Amax: 0.01

SMILES string

[Li+].[Cl-]

InChI

1S/ClH.Li/h1H;/q;+1/p-1

InChI key

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Application


  • The preconditioning of lithium promotes mesenchymal stem cell-based therapy for the degenerated intervertebral disc via upregulating cellular ROS: This study explores the use of lithium chloride in enhancing the efficacy of mesenchymal stem cells for intervertebral disc regeneration. Lithium chloride′s role in modulating cellular responses and oxidative stress mechanisms presents a potential application in developing advanced IVD (In Vitro Diagnostics) products that rely on cellular technologies (Zhu et al., 2021).


Other Notes

Precipitation of RNA; Transformation of intact yeast cells treated with alkali cations


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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D.M. Wallace
Methods in Enzymology, 152, 48-48 (1987)
C Auffray et al.
European journal of biochemistry, 107(2), 303-314 (1980-06-01)
A procedure is described for the large-scale purification of light (L) and heavy (H) chain mRNAs from plasmacytomas produced in mice. Intact RNA is selectively precipitated in high yield from frozen tumors homogenized in 3 M LiCl and 6 M
G Cathala et al.
DNA (Mary Ann Liebert, Inc.), 2(4), 329-335 (1983-01-01)
A method for isolation of large, translationally active RNA species is presented. The procedure involves homogenization of cells or tissues in 5 M guanidine monothiocyanate followed by direct precipitation of RNA from the guanidinium by 4 M LiCl. Modifications are