Saltar al contenido
Merck

Documentos clave

Ver Toda la documentación

PHR1022

Butylparaben

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

4-Hydroxybenzoic acid butyl ester

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas

Acerca de este artículo

Fórmula empírica (notación de Hill):
C11H14O3
Número CAS:
94-26-8
Peso molecular:
194.23
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
202-318-7
MDL number:
MFCD00016478
Beilstein/REAXYS Number:
1103741
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. B1217000, traceable to USP 1084000

API family

parabens

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O(CCCC)C(=O)c1ccc(cc1)O

InChI

1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3

InChI key

QFOHBWFCKVYLES-UHFFFAOYSA-N

General description

Butylparaben is a compound, which belongs to the class of parabens.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

Butylparaben may be used as an internal standard in the analysis of aspirin and warfarin in pharmaceutical formulations using reversed-phase high performance liquid chromatography (RP-HPLC).
Butylparaben may be used as a reference standard for the determination of the analyte in cosmetics, food samples and human breast cancerous tissue by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7759 in the slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Butylparaben

pictograms

Corrosion
GHS05

signalword

Danger

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Hazard Classifications

ED HH 1 - Eye Dam. 1 - Skin Irrit. 2

Certificados de análisis (COA)

Busque los certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto, justo después de las palabras «Lote» o «Batch».

¿Necesita un COA de muestra?

Esto es un Certificado de análisis (COA) de muestra y es posible que no represente un lote de fabricación reciente para este producto específico.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

GC-MS method for the determination of paraben preservatives in the human breast cancerous tissue.
Shanmugam G, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 96(2), 391-396 (2010)
Development and validation of a reversed-phase liquid chromatographic method for analysis of aspirin and warfarin in a combination tablet formulation
Montgomery RE, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15, 73-82 (1996)
Effects of butylparaben on the male reproductive system in rats
Oishi S
Toxicology and Industrial Health, 17, 31-39 (2001)
Ver todos los artículos relacionados