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PHR1816

Furosemide Related Compound B

Name: Furosemide Related Compound B
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

4-Chloro-5-sulfamoylanthranilic acid, 4-CHLORO-5- SULFAMOYLANTHRANILIC ACID

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Fórmula empírica (notación de Hill):

C₇H₇ClN₂O₄S

Número CAS:

3086-91-7

Peso molecular:

250.66

UNSPSC Code:

41116107

NACRES:

NA.24

EC Number:

221-408-7

MDL number:

MFCD03423689

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Propiedades

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1287030

API family

furosemide

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

mp

267 °C (dec.) (lit.)

application(s)

pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

Nc1cc(Cl)c(cc1C(O)=O)S(N)(=O)=O

InChI

1S/C7H7ClN2O4S/c8-4-2-5(9)3(7(11)12)1-6(4)15(10,13)14/h1-2H,9H2,(H,11,12)(H2,10,13,14)

InChI key

QQLJBZFXGDHSRU-UHFFFAOYSA-N

Descripción

General description

Furosemide Related Compound B is an impurity of the loop diuretic drug, furosemide. Furosemide is generally used to treat fluid retention in people with heart failure, liver cirrhosis or kidney disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Furosemide Related Compound B may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC2893 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Hazard Classifications

Aquatic Chronic 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque los certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto, justo después de las palabras «Lote» o «Batch».

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The analysis of 4-chloro-5-sulfamoylanthranilic acid in the bulk material and pharmaceutical preparations of furosemide by a high-performance liquid chromatographic method

Rapaka RS, et al.

International Journal of Pharmaceutics, 11(3), 237- 247 (1982)

Furosemide

StatPearls [Internet] (2019)