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PHR1940

Aspirin Impurity D

Name: Aspirin Impurity D
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid, Acetylsalicylsalicylic acid, 2-Carboxyphenyl o-acetylsalicylate

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Fórmula empírica (notación de Hill):

C₁₆H₁₂O₆

Número CAS:

530-75-6

Peso molecular:

300.26

UNSPSC Code:

41116107

NACRES:

NA.24

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Propiedades

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0001161

API family

aspirin

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O(c1c(cccc1)C(=O)Oc2c(cccc2)C(=O)O)C(=O)C

InChI

1S/C16H12O6/c1-10(17)21-14-9-5-3-7-12(14)16(20)22-13-8-4-2-6-11(13)15(18)19/h2-9H,1H3,(H,18,19)

InChI key

DDSFKIFGAPZBSR-UHFFFAOYSA-N

Descripción

General description

Aspirin Impurity D is an impurity of the antiplatelet drug aspirin, and one of the major antithrombogenic agent widely used for the prevention of heart attacks and stroke.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Aspirin may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric techique and reversed-phase high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC1066 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque los certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto, justo después de las palabras «Lote» o «Batch».

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Simultaneous determination of clopidogrel and aspirin in pharmaceutical dosage forms

Mishra P and Dolly A

Indian Journal of Pharmaceutical Sciences, 68(3) (2006)

Rapid and simultaneous determination of aspirin and dipyridamole in pharmaceutical formulations by reversed-phase high performance liquid chromatography (RP-HPLC) method

Prakash K, et al.

African Journal of Pharmacy and Pharmacology, 5(2), 244-251 (2011)