R5010
Resveratrol
≥99% (HPLC)
동의어(들):
3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C14H12O3
CAS 번호:
Molecular Weight:
228.24
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
biological source
plant root (bushy knotweed)
Quality Segment
assay
≥99% (HPLC)
form
powder
solubility
acetone: 50 mg/mL, clear, faintly yellow
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2
InChI
1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChI key
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Gene Information
human ... AR(367), CYP1A2(1544), ESR1(2099), SIRT1(23411)
mouse ... Nos2(18126)
rat ... Esr1(24890)
Application
Resveratrol has been used:
- in entrapment experiment
- to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II
- as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry
Selective inhibitor of COX−1.
Biochem/physiol Actions
Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events.
Preparation Note
Soluble in ethanol, DMSO, and acetone. Only very slightly soluble in water (3 mg/100 mL).
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저장 등급
11 - Combustible Solids
flash_point_f
>392.0 °F - closed cup - (External MSDS)
flash_point_c
> 200.0 °C - closed cup - (External MSDS)
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3