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Merck

HCVD1MAG-67K

MILLIPLEX® Human Cardiovascular Disease Panel

Configurable Human CVD 12-Plex Panel 1

別名:

CVD assay snapshot, CVD multiplex product sheet, cardiac injury biomarker panel, heart failure detection kit, human CVD assay overview, human cardiac biomarker info, human cardiovascular panel summary, human cardiovascular research tool, vascular inflammation marker listing

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この商品について

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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製品名

MILLIPLEX® Human Cardiovascular Disease Panel,

description

Configurable Human CVD 12-Plex Panel 1

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

plasma
cell culture supernatant(s)

assay range

accuracy: 100%
(CK-MB), accuracy: 102%
(LIGHT), accuracy: 102%
(Oncostatin (OSM)), accuracy: 103%
(CXCL6/GCP-2), accuracy: 96%
(FABP3), accuracy: 96%
(Placental Growth Factor (PlGF)), accuracy: 97%
(NT proBNP), standard curve range: 137.2-100,000 pg/mL
(FABP3), standard curve range: 2.7-2,000 pg/mL
(Placental Growth Factor (PlGF)), standard curve range: 34.3-25,000 pg/mL
(NT proBNP, CXCL16, Endocan-1 (ESM-1), LIGHT), standard curve range: 6.9-5,000 pg/mL
(CXCL6, Oncostatin (OSM)), standard curve range: 68.6-50,000 pg/mL
(BNP, CK-MB, Troponin I (TnI)), standard curve range: 685.9-500,000 pg/mL
(FABP4), inter-assay cv: <20%
intra-assay cv: <10%

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Cardiovascular disease involves a complex network of biological processes including myocardial stress, vascular inflammation, endothelial dysfunction, and metabolic imbalance. This set of biomarkers—BNP, NT-proBNP, CK-MB, CXCL6/GCP-2, CXCL16, Endocan-1 (ESM-1), FABP3, FABP4, LIGHT, Oncostatin-M (OSM), Placental Growth Factor (PlGF), and Troponin I (TnI)—captures key indicators of cardiac injury, inflammation, and vascular remodeling. These analytes are widely studied in the context of heart failure, atherosclerosis, myocardial infarction, and cardiometabolic disorders, making them essential for translational and clinical cardiovascular research.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 12 analytes in human serum, plasma, or cell/tissue culture supernatants.

Analytes included: BNP, NT-proBNP, CK-MB, CXCL6/GCP-2, CXCL16, Endocan-1 (ESM-1), FABP3, FABP4, LIGHT, Oncostatin-M (OSM), Placental Growth Factor (PlGF), Troponin I (TnI)

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Targets biomarkers associated with cardiac stress, vascular inflammation, and endothelial dysfunction
  • Includes 12 analytes relevant to heart failure, myocardial injury, and atherosclerosis
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with human serum, plasma, and cell/tissue culture supernatants
  • Designed for research in cardiovascular disease, metabolic syndrome, and inflammatory conditions
Benefits:
  • Provides a comprehensive profile of cardiovascular and inflammatory biomarkers
  • Supports investigation of disease mechanisms in heart failure, ischemia, and vascular remodeling
  • Facilitates evaluation of therapeutic interventions and biomarker-based risk stratification
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for translational and clinical research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

保管分類

10 - Combustible liquids

wgk

WGK 3


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Kévin Contrepois et al.
Cell, 181(5), 1112-1130 (2020-05-30)
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune pathways. Although studies have examined selected changes in these pathways, the system-wide molecular response to an acute bout of exercise has not been fully characterized. We performed longitudinal
Amit Saxena et al.
Journal of the American College of Cardiology, 66(8), 930-939 (2015-08-22)
Cardiac manifestations of neonatal lupus (cardiac NL) include congenital heart block and cardiomyopathy. Several candidate biomarkers were evaluated in cases at risk for cardiac NL on the basis of potential roles in inflammation, fibrosis, and cardiac dysfunction: C-reactive protein (CRP);

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