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BioContinuum™ Platform for Next Generation Bioprocessing

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BioContinuum™ Platform

Continuous Processing:
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ProCellics™ Raman Analyzer with Bio4C™ PAT Raman Software

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Today’s mammalian cell culture’s monitoring strategies lack real-time measurement and rely on daily manual sampling and feeding, which increases the risk of contamination and batch failures.

In-line and real-time measurement of process parameters and quality attributes provide improved process understanding, leading to a more consistent product quality.

ProCellics™ Raman Analyzer with Bio4C™ PAT Raman software is a PAT platform for in-line and real-time monitoring of cell culture process parameters and quality attributes for greater process optimization, control and reproducibility. It also helps to implement a nutrient control loop strategy, a first step towards automation.


  • Process improvement: Monitor in real-time process parameters and quality attributes for greater process understanding and optimization, control and reproducibility increase.
  • Process automation: Reduce off-line sampling and manual feeding via an automated nutrient control loop strategy. Decrease the risk of contamination and minimize the risk of batch failures.
  • Easy-to-use: Specifically designed for the bioprocessing industry, easy to use hardware and software for both Raman experts and team members unfamiliar with Raman technology and multivariate analytics.
  • Easy-to-implement: Get comprehensive support and services from our experienced engineers and chemometric bioprocessing experts to ensure successful implementation and use.