165344
1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide
for peptide synthesis
Synonym(s):
EDC methiodide
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About This Item
Linear Formula:
C2H5N=C=N(CH2)3N(CH3)3I
CAS Number:
Molecular Weight:
297.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
245-095-1
MDL number:
Product Name
1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide,
form
powder
Quality Level
reaction suitability
reaction type: Coupling Reactions
mp
97-99 °C (lit.)
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
SMILES string
[I-].CCN=C=NCCC[N+](C)(C)C
InChI
1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI key
AGSKWMRPXWHSPF-UHFFFAOYSA-M
Application
- Crosslinking agent
Reactant for:
- Amide bond forming (amidation) crosslinking reactions
Water-soluble carboxyl modifying reagent for proteins.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Cyrille Garnier et al.
Biochemistry, 41(39), 11770-11778 (2002-09-25)
The 90 kDa heat-shock protein (Hsp90) is one of the major stress proteins whose overall structure remains unknown. In this study, we investigated the influence of divalent cations Mg(2+) and Ca(2+) on the hydrodynamic properties and quaternary structure of Hsp90.
E Schaffitzel et al.
Biological chemistry, 382(8), 1235-1243 (2001-10-11)
In Escherichia coli, the ribosome-associated Trigger Factor (TF) cooperates with the DnaK system in the folding of newly synthesized cytosolic polypeptides. Here we investigated the functional relationship of TF and DnaK by comparing various functional properties of both chaperones. First
G Csaba et al.
Cell biology international, 30(5), 412-415 (2006-03-21)
The amount and localization of three hormones (histamine, endorphin and triiodothyronine [T(3)]) was measured in male and female rat peritoneal cells (lymphocytes, mast cells, monocyte-macrophage-granulocyte group [mo-gran]) using flow cytometry as well as confocal microscopy after paraformaldehyde (PFA) or EDAC