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Merck

217638

Sodium iodide

ReagentPlus®, ≥99%

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About This Item

Linear Formula:
NaI
CAS Number:
7681-82-5
Molecular Weight:
149.89
NACRES:
NA.21
PubChem Substance ID:
329752204
UNSPSC Code:
12352302
EC Number:
231-679-3
MDL number:
MFCD00003532
Assay:
≥99%
Form:
powder
Solubility:
water: soluble(lit.)

Key Documents

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vapor density

>1 (vs air)

Quality Level

100

product line

ReagentPlus®

assay

≥99%

form

powder

impurities

<1.0% water

pH

6-9 (20 °C, 50 g/L)

mp

661 °C (lit.)

solubility

water: soluble(lit.)

SMILES string

[Na+].[I-]

InChI

1S/HI.Na/h1H;/q;+1/p-1

InChI key

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

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General description

Sodium iodide is an ionic compound that can be prepared by treating sodium hydroxide or sodium carbonate with hydriodic acid. It is a versatile reagent used as an iodide source in organic synthesis.

Application

Sodium iodide can be used as a catalyst :
  • To synthesize α-alkoxylated ketones.
  • For N-tert-butoxy carbonylation of amines.
It can also be used as a reagent for the conversion of aryl amines to aryl iodides.

Other Notes

Go to Redi-Dri™ Product Listing 793558

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

flash_point_f

Not applicable

flash_point_c

Not applicable

target_organs

Thyroid

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

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Eagleson M.
Concise Encyclopedia Chemistry, 648-648 (1994)
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent.
Olah GA, et al.
The Journal of Organic Chemistry, 44(8), 1247-1251 (1979)
The Chesapeake Bay Institute technique for the Winkler dissolved oxygen method.
Carpenter JH.
Limnology and Oceanography, 10(1), 141-143 (1965)
Eagleson M.
Concise Encyclopedia Chemistry, 999-999 (1994)
Caroline Serrano-Nascimento et al.
Molecular and cellular endocrinology, 349(2), 154-161 (2011-10-18)
Iodide excess acutely downregulates NIS mRNA expression, as already demonstrated. PCCl3 cells treated or not with NaI, NaI+NaClO(4) or NaI+Methimazole, for 30 min to 24 h, were used to further explore how iodide reduces NIS gene expression. NIS mRNA expression
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