49781
Glycerol solution
83.5-89.5% (T)
Synonym(s):
1,2,3-Propanetriol
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About This Item
Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
Molecular Weight:
92.09 (anhydrous basis)
UNSPSC Code:
50161901
NACRES:
NA.28
PubChem Substance ID:
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
Assay:
83.5-89.5% (T)
Technique(s):
MALDI-MS: suitable
Bp:
182 °C/20 mmHg (lit.)
InChI key
PEDCQBHIVMGVHV-UHFFFAOYSA-N
InChI
1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
SMILES string
OCC(O)CO
assay
83.5-89.5% (T)
form
viscous liquid
greener alternative product characteristics
Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.
sustainability
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technique(s)
MALDI-MS: suitable
impurities
10.5-16.5% water
ign. residue
≤0.01% (as SO4)
bp
182 °C/20 mmHg (lit.)
density
1.252 g/mL at 25 °C (lit.)
greener alternative category
Quality Level
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General description
Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.
Application
Glycerol solution has been used:
- in the preparation of blood mimicking fluid
- in epidermis mimicking films
- as a constituent of nuclei storage buffer
Biochem/physiol Actions
Glycerol has been used as
- a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
- a fuel during designing enzymatic biofuel cell.
- a liquid composite matrix with 4-HCCA and 3-aminoquinoline for analysis of neutral and acidic glycans.
- a matrix for fast atom bombardment MS.
- may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.
Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.
Other Notes
Substrate for the assay of glycerokinase; glycerol dehydratase; glycerol oxidase
wgk
WGK 1
ppe
Eyeshields, Gloves
Storage Class
10 - Combustible liquids
flash_point_f
320.0 °F - closed cup
flash_point_c
160 °C - closed cup
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Multilayered tissue mimicking skin and vessel phantoms with tunable mechanical, optical, and acoustic properties
Chen AI, et al.
Medical Physics, 43(6), 3117-3131 (2016)
H.U. Bergmeyer, ed.
Methods of Enzymatic Analysis, 2, 216-216 (1983)
Glycerol oxidase from Aspergillus japonicus.
T Uwajima et al.
Methods in enzymology, 89 Pt D, 243-248 (1982-01-01)
Automated end-to-end blood testing at the point-of-care: Integration of robotic phlebotomy with downstream sample processing
Balter ML, et al.
Technology, 1-8 (2018)
Glycerol dehydratase from Aerobacter aerogenes.
B C Johnson et al.
Methods in enzymology, 42, 315-323 (1975-01-01)
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