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48-612MAG

MILLIPLEX® Akt/mTOR Signaling Panel

Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel

Synonym(s):

Magnetic bead assay, Akt mTOR total assay, Akt total protein, PI3K pathway assay, kinase total assay, mTOR total detection, multiplex total ELISA, total protein panel, total signaling proteins

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Product Name

MILLIPLEX® Akt/mTOR Signaling Panel,

Quality Segment

200

description

Premixed Akt/mTOR Total 11-Plex Cell Signaling Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell lysate

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

This panel targets total expression of key proteins in the PI3K/Akt/mTOR signaling pathway, which regulates cell growth, metabolism, and survival. It includes total levels of Akt isoforms, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6. These proteins are frequently altered in cancer, diabetes, and neurodegenerative diseases.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 11 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: Akt (Total), GSK3α (Total), GSK3β (Total), IGF-1R (Total), IR (total), IRS1 (Total), mTOR (Total), p70S6K (Total), PTEN (Total), RPS6 (Total), TSC2 (Total)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™Control Assays).

Features and Benefits

  • Simultaneously detect total expression of 11 proteins in the PI3K/Akt/mTOR signaling pathway
  • Includes Akt1, Akt2, Akt3, mTOR, PTEN, GSK3α/β, IRS1, IGF1R, IR, p70S6K, and RPS6
  • Magnetic bead-based format ensures reproducibility and efficient processing
  • Compatible with cell lysates from cancer, metabolic, and signaling studies
  • Ideal for oncology, metabolism, and cell biology research
  • Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corporation
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Exclamation mark
GHS07

Storage Class

10-13 - German Storage Class 10 to 13

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2

wgk

WGK 2

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