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AB5818-200UL Anti-Potassium Channel Kir4.1 Antibody

Detect Potassium Channel Kir4.1 using this Anti-Potassium Channel Kir4.1 Antibody validated for use in WB.

Anti-Potassium Channel Kir4.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Ion Channels & Transporters Gene Symbol: KCNJ10, KIR1.2, Kir4.1, KCNJ13-PEN, Kir1.2, KIR4.1, BIRK-10 UniProt Number: P78508
AB5818-200UL
200 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB5818-200UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Potassium Channel Kir4.1 Antibody
      References
      Product Information
      FormatAffinity Purified
      Control
      • CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile distilled water. For negative control, preincubate 1 μg of protein with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationAffinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Quality SegmentMQ100
      Applications
      ApplicationDetect Potassium Channel Kir4.1 using this Anti-Potassium Channel Kir4.1 Antibody validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1:400 using ECL on rat brain membranes.

      Dilutions should be made using a carrier protein such as BSA (1-3%)

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide corresponding to amino acids 356-375 of rat, mouse or human Kir4.1.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Kir4.1. The epitope does not share homology with any other known proteins.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.
      Gene Symbol
      • KCNJ10
      • KIR1.2
      • Kir4.1
      • KCNJ13-PEN
      • Kir1.2
      • KIR4.1
      • BIRK-10
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P78508 # May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
      SIZE: 379 amino acids; 42508 Da
      SUBUNIT: Seems to form heterodimer with Kir5.1/KCNJ16. Interacts with INADL (By similarity).
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      SIMILARITY: SwissProt: P78508 ## Belongs to the inward rectifier-type potassium channel family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Catalogue Number GTIN
      AB5818-200UL 04053252739286

      Documentation

      Anti-Potassium Channel Kir4.1 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Potassium Channel Kir4.1 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2135070 2135070
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2387757 2387757
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2433272 2433272
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2469333 2469333
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2117130 2117130
      RABBIT ANTI-Kir4.1 -2519339 2519339
      RABBIT ANTI-Kir4.1 -2670370 2670370
      RABBIT ANTI-Kir4.1 -2710743 2710743
      RABBIT ANTI-Kir4.1 -2728433 2728433
      RABBIT ANTI-Kir4.1 -2736672 2736672
      Show more

      Data Sheet

      Title
      RABBIT ANTI-Kir4.1 AFFINITY PURIFIED POLYCLONAL ANTIBODY

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies