Neuroscience Biomarker Assays Using Luminex® Technology

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A biomarker of a neurological disorder is, by definition, differentially expressed between a normal subject’s nervous system and that of a subject bearing a neurological disorder. Traditionally, neuroscience biomarkers could only be detected after a subject already exhibit cognitive decline or other symptoms of disease; however, recent, sensitive assays have shown biomarkers to be present even in advance of other symptoms.

Bring Your Neuroscience Biomarkers to Life with MILLIPLEX® MAP Multiplex Assays

No single biomarker has the power to give you a complete picture of nervous system functions such as perception, cognition, motor and homeostatic control, or of disorders such as Alzheimer’s and Parkinson’s disease, multiple sclerosis and amyotrophic lateral sclerosis (ALS).

Bead-based MILLIPLEX® MAP neuroscience immunoassays, using trusted Luminex xMAP® technology, enable multivariate analysis of the processes that underlie neural development, homeostasis and pathogenesis—all this while conserving your precious samples.

MILLIPLEX® MAP multiplex assays enable you to measure neuroscience-related biomarkers, of which a subset are shown below. Download the Analyte Quarterly brochure for a complete, updated list of assays.

Neurodegenerative Disease*:

Apo E	sICAM-1	GDNF
Amyloid β40	sVCAM-1	sRAGE
Amyloid β42	PAI-1	S100B

*Selected analytes shown

Neurological Disorders*:

Tau	Park7	AGP
Phospho Tau	NGFβ	CP
Park5	NSE	SAP

*Selected analytes shown

Neuropeptide/Neurohormone Signaling*:

α-MSH	Cortisol	Melatonin
Orexin A	Oxytocin	Substance P

*Selected analytes shown

Merck’s portfolio of Luminex assays includes analytes in these research areas:

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