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Merck

MAB1912

Anti-Collagen Type I (COL1A1) Antibody

CHEMICON®, rat monoclonal, M-58

Synonym(s):

Anti-Procollagen Antibody, Clone M-58 Anti-Procollagen, Type I Procollagen Detection

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
M-58, monoclonal
Species reactivity:
human
Application:
IHC
Citations:
41

Key Documents

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Product Name

Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®

isotype

IgG2α

biological source

rat

antibody form

culture supernatant

clone

M-58, monoclonal

species reactivity

human

should not react with

rat, hamster, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)

NCBI accession no.

NM_000088.3

UniProt accession no.

P02452

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... COL1A1(1277)

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Application

Detect Procollagen Type I using this Anti-Procollagen Type I Antibody, N-terminus, clone M-58 validated for use in IH(P).
Immunohistochemistry: 1:10,000-1:50,000 (fresh frozen tissue sections.)

Suitable for formaldehyde/formalin fixed paraffin sections, suggested starting dilution 1:100-1:1000, after treatment with 1% trypsin, 20 minutes at room temperature. Does not stain mature collagen fibers in tissue. Localized intracellularly in cells producing pro-collagen I. Not recommended for Western Blots Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes Human pro-collagen I. MAB1912 labels the amino-terminal pro-peptide.

Analysis Note

Control
Skin tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion.
Yunker, CK; Golembieski, W; Lemke, N; Schultz, CR; Cazacu, S; Brodie, C; Rempel, SA
International Journal of Cancer. Journal International Du Cancer null
Platelet-rich fibrin versus albumin in surgical wound repair: a randomized trial with paired design.
Danielsen, Patricia L, et al.
Annals of Surgery, 251, 825-831 (2010)
Dose-dependent impairment of collagen deposition by topical granulocyte-macrophage colony-stimulating factor in human experimental wounds.
Lars N Jorgensen, Magnus S Agren, S?ren M Madsen, Finn Kallehave, Faranak Vossoughi et al.
Annals of Surgery null
M D Rekhter et al.
The American journal of pathology, 143(6), 1634-1648 (1993-12-01)
Because collagen is a major component of the human atherosclerotic plaque, factors controlling collagen synthesis may have a profound influence on the volume growth of these intimal lesions. In human arteries, we compared normal vs atherosclerotic media vs intimas for
John P McCook et al.
Clinical, cosmetic and investigational dermatology, 9, 167-174 (2016-08-16)
To examine the effect of sodium copper chlorophyllin complex on the expression of biomarkers of photoaged dermal extracellular matrix indicative of skin repair. Following a previously published 12-day clinical assessment model, skin biopsy samples from the forearms of four healthy
View All Related Papers

Global Trade Item Number

SKUGTIN
MAB191204053252465383

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