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Merck

G4626

L-Glutathione oxidized disodium salt

≥98%, suitable for HPLC

Synonym(s):

GSSG

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About This Item

Empirical Formula (Hill Notation):
C20H30N6Na2O12S2
CAS Number:
Molecular Weight:
656.59
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
6265389
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Product Name

L-Glutathione oxidized disodium salt, ≥98%, powder

Quality Level

assay

≥98%

form

powder

technique(s)

HPLC: suitable

impurities

ethanol, essentially free

color

white to off-white

storage temp.

−20°C

SMILES string

[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O

InChI

1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1

InChI key

DRFILBXQKYDTFW-JIWRMXRASA-L

Application

L-Glutathione oxidized disodium salt has been used in 5,5′-dithiobis-(2-nitrobenzoic acid) (DTNB)/glutathione reductase enzyme recycling method to determine plasma or tissue glutathione levels. It has also been used in NADPH-dependent glutathione disulfide reduction assay.

Biochem/physiol Actions

Oxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress. Oxidized L-Glutathione may be converted to L-glutathione by various reducing systems.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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