G5146
D-(+)-Glucose
Hybri-Max™, powder, BioReagent, suitable for hybridoma
Synonym(s):
Dextrose
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About This Item
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
NACRES:
NA.75
EC Number:
200-075-1
Beilstein/REAXYS Number:
1724615
InChI key
WQZGKKKJIJFFOK-DVKNGEFBSA-N
InChI
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
SMILES string
OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
biological source
maize
grade
Hybri-Max™
product line
BioReagent
assay
≥99.5%
form
powder
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
mp
150-152 °C (lit.)
solubility
H2O: 2g + 15 mL (Tested)
Quality Level
Gene Information
human ... PYGM(5837)
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Application
D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.
Biochem/physiol Actions
Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.
General description
Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.
Preparation Note
The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
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Novel variant in the PYGM gene causing late-onset limb-girdle myopathy, ptosis, and camptocormia
Cheraud C, et al.
Muscle and Nerve, 57(1), 157-160 (2018)
The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia
Pinacho R, et al.
Schizophrenia Research, 177(1-3), 37-43 (2016)
CDKN1C/p57 kip2 is a candidate tumor suppressor gene in human breast cancer
Larson PS, et al.
BMC Cancer, 8(1), 68-68 (2008)
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
PLoS ONE, 10(3) (2015)
Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
Johansson J, et al.
PLoS ONE, 8(1) (2013)
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