P3655
Poly-L-ornithine hydrobromide
Mol wt 30,000-70,000
Synonym(s):
L-Ornithine homopolymer hydrobromide
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About This Item
Product Name
Poly-L-ornithine hydrobromide, mol wt 30,000-70,000
form
powder
Quality Level
mol wt
30,000-70,000
color
white to off-white
storage temp.
−20°C
SMILES string
[Br-].NC(CCCN)C(=O)O.[H+]
InChI
1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H
InChI key
GWRQMKDBBHFVIZ-UHFFFAOYSA-N
Application
Poly-L-ornithine hydrobromide has been used to coat coverslips in culture vessels for culturing neural progenitor cells. It has also been used to coat culture plates for culturing cerebral cells of mice.
Biochem/physiol Actions
Poly-L-ornithine is a specialized coating that acts as a charge modifier. It is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs.
Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke Kamiya
Biologicals : Journal of the International Association of Biological Standardization (2017)
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Mario Marotta
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FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells
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