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P60205

2-Pyridinealdoxime methiodide

Name: 2-Pyridinealdoxime methiodide
Brand: ALDRICH

99%

Synonym(s):

2-PAM, 2-PAM iodide, Pralidoxime iodide

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About This Item

Empirical Formula (Hill Notation):

C₇H₁₁IN₂O

CAS Number:

94-63-3

Molecular Weight:

266.08

NACRES:

NA.22

PubChem Substance ID:

24898726

UNSPSC Code:

12352100

EC Number:

202-349-6

MDL number:

MFCD00011982

Assay:

99%

Form:

solid

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Properties

Quality Level

200

assay

99%

form

solid

mp

220 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

[I-].C[n+]1ccccc1\C=N\O

InChI

1S/C7H8N2O.HI/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H

InChI key

QNBVYCDYFJUNLO-UHFFFAOYSA-N

Gene Information

human ... ACHE(43)

Description

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Editor's Highlight: Spatiotemporal Progression and Remission of Lesions in the Rat Brain Following Acute Intoxication With Diisopropylfluorophosphate.

Sílvia Sisó et al.

Toxicological sciences : an official journal of the Society of Toxicology, 157(2), 330-341 (2017-03-23)

Similar to organophosphate (OP) nerve agents, diisopropylfluorophosphate (DFP) rapidly and irreversibly inhibits acetylcholinesterase, leading to convulsions that can progress to status epilepticus (SE). However, in contrast to the OP nerve agents, the long-term consequences of DFP-induced SE are not well

Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin.

Kimberly D Spradling et al.

Journal of neuroinflammation, 8, 84-84 (2011-07-23)

Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well understood. To help determine these pathways, we previously used

Exploring pralidoxime chloride as a universal electrochemical probe for organophosphorus pesticides detection.

Qiqi Zheng et al.

Analytica chimica acta, 982, 78-83 (2017-07-25)

An electrochemical method based on non-enzymatic inhibition for the determination of organophosphorus pesticide (OPPs) using pralidoxime chloride (PAM-Cl) as a universal electrochemical probe was reported. Cyclic voltammetry was performed to characterize the redox properties of pralidoxime and OPPs. Differential pulse

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