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Merck

16301

D-(+)-Glucose monohydrate

meets analytical specification of Ph. Eur., BP, Ph Franç., 97.5-102.0% anhydrous basis(HPLC)

Synonym(s):

Dextrose monohydrate

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About This Item

Empirical Formula (Hill Notation):
C6H12O6 · H2O
CAS Number:
14431-43-7
Molecular Weight:
198.17
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
57647555
EC Number:
218-914-5
Beilstein/REAXYS Number:
5250278
MDL number:
MFCD00149450

Key Documents

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InChI key

SPFMQWBKVUQXJV-BTVCFUMJSA-N

InChI

1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1

SMILES string

O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O

assay

97.5-102.0% anhydrous basis (HPLC)

form

powder

optical activity

[α]20/D +52.5 to +53.3°, c = 10% in H2O (calc. on anhydrous subst.)

quality

meets analytical specification of Ph. Eur., BP, Ph Franç.

impurities

residual solvents, complies, 97.5-102.0% anhydrous basis (HPLC)

ign. residue

≤0.1% (as SO4)

color

white

useful pH range

6-7 (20 °C, 100 g/L)

mp

~83  °C (181 °F )

solubility

H2O: 10g/5 mL, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg, sulfite (SO32-): ≤15 ppm

cation traces

Al: ≤0.5 mg/kg, As: ≤1 mg/kg, Ba:, in accordance, Ca: ≤200 mg/kg, Pb: ≤0.5 mg/kg

Quality Level

200

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Application

D-(+)-Glucose monohydrate has been used as a test compound for studying its dehydration kinetics by using THz time-domain spectroscopy (THz-TDS).

Biochem/physiol Actions

D-(+)-Glucose is a common natural sugar involved in key cellular processes of energy production, glycosylation and formation of glycans that provide structure to cells. Glucose is involved in post-translational modifications of proteins by glycation or non-enzymatic glycosylation of proteins at the lysine residues. Glycation is detrimental and results in complications associated with diabetes mellitus, alzheimer′s disease, aging and cataract.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
STBK8903
STBK7210
STBK4975
STBK4233
STBK1909

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Dehydration kinetics of D-glucose monohydrate studied using THz time-domain spectroscopy.
Hai-Bo Liu
Chemical Physics Letters, 429 (2006)
Fotini A Trikka et al.
Microbial cell factories, 14, 60-60 (2015-04-24)
Terpenoids (isoprenoids) have numerous applications in flavors, fragrances, drugs and biofuels. The number of microbially produced terpenoids is increasing as new biosynthetic pathways are being elucidated. However, efforts to improve terpenoid production in yeast have mostly taken advantage of existing
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
Thornalley PJ et al
The Biochemical Journal, 344 (1999)
Codruta Ignea et al.
Nature communications, 10(1), 3799-3799 (2019-08-25)
Synthetic biology efforts for the production of valuable chemicals are frequently hindered by the structure and regulation of the native metabolic pathways of the chassis. This is particularly evident in the case of monoterpenoid production in Saccharomyces cerevisiae, where the
Codruta Ignea et al.
Scientific reports, 7(1), 8855-8855 (2017-08-20)
Plants synthesize numerous specialized metabolites (also termed natural products) to mediate dynamic interactions with their surroundings. The complexity of plant specialized metabolism is the result of an inherent biosynthetic plasticity rooted in the substrate and product promiscuity of the enzymes
View All Related Papers

Global Trade Item Number

SKUGTIN
16301-1KG04061838747310

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