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Merck

91462

Kollisolv® PEG E 300

greener alternative

Synonym(s):

Poly(ethylene glycol), Lutrol E 300, Macrogol 300, Polyethylene glycol 300, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
NACRES:
NA.25
MDL number:
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form

liquid

Quality Level

mol wt

average Mw 285-315 g/mol (from OH-value (56100*2)/OHZ)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

reducing substances, complies, ≤0.1% sulfated ash, ≤0.25% ethylene glycol and diethylene glycol (sum), ≤1 ppm ethylene oxide, ≤1 ppm lead (verified on random samples only), ≤1.0% water, ≤10 ppm dioxan, ≤15 ppm formaldehyde, ≤5 ppm heavy metals (verified on random samples only), 0.5 g acetic acid (per 100 g), 620 ppm ethylene oxide

pH

4.5-7.0 (50 g/L)

viscosity

80-105 mPa.s(20 °C) (5.4-6.4 CS (98.9°C))

hydroxyl value

340‑394 mg KOH/g

solubility

H2O: 10%, clear, colorless

suitability

complies for acidity or alkalinity

greener alternative category

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.

Other Notes

The PEG E grades of Kollisolv are polyethylene glycols (macrogols) of different molecular weights.

Legal Information

Kollisolv is a registered trademark of BASF


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

428.0 °F - closed cup

flash_point_c

220.00 °C - closed cup



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Scott N Furlan et al.
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D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a