C0158
L-Carnitine inner salt
≥98%
Synonym(s):
(−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin BT
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About This Item
Linear Formula:
(CH3)3N+CH2CH(OH)CH2COO-
CAS Number:
Molecular Weight:
161.20
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
208-768-0
MDL number:
Beilstein/REAXYS Number:
4292315
Product Name
L-Carnitine inner salt, synthetic, ≥98%
biological source
synthetic
Quality Level
assay
≥98%
form
powder
color
white
mp
197-212 °C (lit.)
application(s)
cell analysis
detection
SMILES string
C[N+](C)(C)C[C@H](O)CC([O-])=O
InChI
1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChI key
PHIQHXFUZVPYII-ZCFIWIBFSA-N
Application
L-Carnitine inner salt has been used as a component of an assay medium for Seahorse XF mitochondrial stress assay. It has also been orally administered to tumor-bearing mice, in order to study its effect on the regulation of peroxisome proliferator-activated receptor and thereby to analyse liver inflammatory response.
Biochem/physiol Actions
Carnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment. In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branched chain amino acids.
Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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