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H5659

L-Histidine monohydrochloride monohydrate

Name: <SC>L</SC>-Histidine monohydrochloride monohydrate
Brand: SIGMA

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₆H₉N₃O₂ · HCl · H₂O

CAS Number:

5934-29-2

Molecular Weight:

209.63

UNSPSC Code:

12352209

eCl@ss:

32160406

PubChem Substance ID:

24895703

NACRES:

NA.26

Beilstein/REAXYS Number:

4168261

MDL number:

MFCD00151027

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Properties

Product Name

L-Histidine monohydrochloride monohydrate, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

agency

meets EP testing specifications

product line

BioXtra

assay

98.5-101.0%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

254 °C (dec.) (lit.)

solubility

H₂O: 100 mg/mL

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

Description

Application

L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.

L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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