Skip to Content
Merck

143049

Aldrithiol™-2

98%

Synonym(s):

2,2′-Dithiodipyridine, 2,2′-Dipyridyl disulfide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
2127-03-9
Molecular Weight:
220.31
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24848570
EC Number:
218-343-1
Beilstein/REAXYS Number:
154629
MDL number:
MFCD00006287

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Aldrithiol™-2, 98%

InChI key

HAXFWIACAGNFHA-UHFFFAOYSA-N

InChI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

SMILES string

S(Sc1ccccn1)c2ccccn2

assay

98%

form

solid

mp

56-58 °C (lit.)

solubility

methanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow

functional group

disulfide

storage temp.

2-8°C

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Aldrithiol™-2 was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.
Thiol reagent. Employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.

General description

Aldrithiol™-2 is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Legal Information

Aldrithiol is a trademark of Sigma-Aldrich Co. LLC

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBN9569V
MKCF0416
BCBL4204V
BCBN5308V
BCBP0559V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tetrahedron Letters, 35, 1267-1267 (1994)
Analytical Sciences, 10, 17-17 (1994)
J L Rossio et al.
Journal of virology, 72(10), 7992-8001 (1998-09-12)
Whole inactivated viral particles have been successfully used as vaccines for some viruses, but procedures historically used for inactivation can denature virion proteins. Results have been inconsistent, with enhancement of disease rather than protection seen in some notable instances following
Journal of Chromatography A, 662, 87-87 (1994)
T L Dutka et al.
The Journal of physiology, 589(Pt 9), 2181-2196 (2010-12-01)
S-Nitrosoglutathione (GSNO) is generated in muscle and may S-glutathionylate and/or S-nitrosylate various proteins involved in excitation–contraction (EC) coupling, such as Na+-K+-ATPases, voltage-sensors (VSs) and Ca2+ release channels (ryanodine receptors,RyRs), possibly changing their properties. Using mechanically skinned fibres from rat extensor
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service