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Merck

295906

Poly(ethylene glycol)

greener alternative

average Mn 2,050, chips

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
UNSPSC Code:
12352104
PubChem Substance ID:
24857821
NACRES:
NA.23
MDL number:
MFCD00081839

Key Documents

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Product Name

Poly(ethylene glycol), average Mn 2,050, chips

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

form

chips

mol wt

average Mn 2,050

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

52-54 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

Aligned

Quality Level

200

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

  • Cytotoxicity Study of Polyethylene Glycol Derivatives: Evaluates the cytotoxic effects of various PEG derivatives, important for chemists in pharmaceutical development and safety assessment (Liu et al., 2017).
  • ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles: Introduces a PEG-based method for isolating exosomes, useful for researchers in biomedical and clinical sciences (Rider et al., 2016).

Other Notes

Molecular weight: Mn 1,900-2,200

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

295906-5G: + 295906-VAR: + 295906-250G: + 295906-BULK: + 295906-500G:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0926
BCCH0927
BCCG4863
BCCG4858
BCCF9450

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Chenlu Zhang et al.
PloS one, 12(9), e0184730-e0184730 (2017-09-09)
The economic production of cellulosic biofuel requires efficient and full utilization of all abundant carbohydrates naturally released from plant biomass by enzyme cocktails. Recently, we reconstituted the Neurospora crassa xylodextrin transport and consumption system in Saccharomyces cerevisiae, enabling growth of
Paras R Patel et al.
Journal of neural engineering, 12(4), 046009-046009 (2015-06-03)
Single carbon fiber electrodes (d = 8.4 μm) insulated with parylene-c and functionalized with pTS have been shown to record single unit activity but manual implantation of these devices with forceps can be difficult. Without an improvement in the insertion
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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