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Merck

360627

Poly(vinyl alcohol)

Mw 8,000-10,000, 80% hydrolyzed

Synonym(s):

PAA

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
UNSPSC Code:
12352104
NACRES:
NA.23
MDL number:
MFCD00081922

Key Documents

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SMILES string

C=CO

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

form

crystals

mol wt

Mw 8,000-10,000

falling ball

2.5-3.5 cP, 4 % in H2O(20 °C)(lit.)

mp

250 °C (482 °F)

density

1.19-1.31 g/cm3

application(s)

advanced drug delivery
filtration

Quality Level

200

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General description

PVA is a water soluble biocompatible polymer. It minimizes protein adsorption on its surface due to steric stabilization effect, unique solution properties and molecular conformation in aqueous form. The steric repulsion occurs due to osmotic pressure and elastic restoring forces competing with the van der Waal′s attraction between water soluble polymers and protein.

Application

PVA is used:
  • In the cell collection medium for determining cellular function of mouse oocytes and eggs cells.
  • As a coating and stabilizer in the preparation of drug loaded microparticles.
  • In the preparation of biocompatible polymer blends of chitosan and poly (vinyl) alcohol.
  • In the synthesis of bioactive polymer blends of poly(lactic acid)/poly(vinyl-alcohol)-chitosan.
  • In developing chitosan-polyvinyl alcohol-bioactive glass composite membranes.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

360627-1KG: + 360627-500G: + 360627-25G: + 360627-VAR: + 360627-BULK:

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Ezequiel de Souza Costa-Júnior et al.
Journal of materials science. Materials in medicine, 20(2), 553-561 (2008-11-07)
In the present work we report the synthesis, characterization, and preliminary biocompatibility of polymer blends based on Chitosan and poly(vinyl alcohol) (PVA) with low degree of hydrolysis and chemically crosslinked by glutaraldehyde for potential application on skin tissue repairing. The
Preparation and characterization of chitosan/poly(vinyl alcohol) chemically crosslinked blends for biomedical applications
Ezequiel S. Costa-Junior, et al.
Carbohydrate Polymers, 76(3) null
Low protein adsorption biomaterials from polymer blends
Ding YS and Qin C
SPE/ANTEC 1996 Proceedings null
Ternary melt blends of poly(lactic acid)/poly(vinyl alcohol)-chitosan
Grande R, et al.
Industrial Crops and Products (2015)
Luisa L S Dias et al.
Biomatter, 1(1), 114-119 (2011-07-01)
The tissue engineering strategy is a new approach for the regeneration of cementum, which is essential for the regeneration of the periodontal tissue. This strategy involves the cell cultures present in this tissue, called cementoblasts, and located on an appropriate
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