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Merck

440140

(3-Aminopropyl)triethoxysilane

99%

Synonym(s):

3-Triethoxysilylpropylamine, APTES, APTS

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About This Item

Linear Formula:
H2N(CH2)3Si(OC2H5)3
CAS Number:
919-30-2
Molecular Weight:
221.37
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
24867571
EC Number:
213-048-4
Beilstein/REAXYS Number:
1754988
MDL number:
MFCD00008207

Key Documents

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InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

SMILES string

CCO[Si](CCCN)(OCC)OCC

assay

99%

form

liquid

bp

217 °C/760 mmHg (lit.)

density

0.946 g/mL at 25 °C (lit.)

Quality Level

200

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General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.

Application

Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.
Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO2 to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications. It can be used to functionalize silane diazirine for fiber optic biosensor application. Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.
Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

199.4 °F - closed cup

flash_point_c

93 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

440140-500ML: + 440140-100ML: + 440140-VAR: + 440140-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR0742
MKCQ4144
WXBD5497V
MKCP6975
MKCN8433

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Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte.
Ye Kehan, et al
Sensors and Actuators B, Chemical, 256(1), 234-242 (2018)
Hollow microcarriers for large-scale expansion of anchorage-dependent cells in a stirred bioreactor.
YekrangSafakar, et al.
Biotechnology and Bioengineering, 115(7), 1717-1728 (2018)
Platinum nanoparticles homogenously decorating multilayered reduced graphene oxide for electrical nanobiosensor applications.
Proa-Coronado, et al.
Thin Solid Films, 658(1), 54-60 (2018)
Effect of divalent versus monovalent cations on the MS2 retention capacity of amino-functionalized ceramic filters.
Bartels J, et al.
Physical Chemistry Chemical Physics, 20(16), 11215-11223 (2018)
Functionalisation of Detonation Nanodiamond for Monodispersed, Soluble DNA-Nanodiamond Conjugates Using Mixed Silane Bead-Assisted Sonication Disintegration.
Edgington, et al.
Scientific Reports, 8(1), 728-728 (2018)
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