457620
Polyglycolide
inherent viscosity 1.4dL/g
Synonym(s):
PGA, Poly(glycolic acid)
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About This Item
Linear Formula:
(C2H4O3)n
CAS Number:
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
Quality Level
form
solid
degradation timeframe
6-12 months
inherent viscosity
1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)
transition temp
Tm 220-230 °C
solubility
hexafluoroisopropanol: soluble
density
1.53 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
OCC(O)=O
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
General description
Biodegradable polymer
Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.
Application
medical device
Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
Preparation Note
To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
ポリラクチドおよびポリグリコリドを含む脂肪族ポリエステルは、医療用途に広く使用されている生分解性ポリマーです。
ラクチドとグリコリドからなる生分解性ホモポリマー/共重合体（RESOMER）の構造、性質、応用について解説しています。
AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.
Effect of dsDNA wrapped single-walled carbon nanotubes on the thermal and mechanical properties of polycaprolactone and polyglycolide fiber blend composites
Spearman SS
Polymer, 56(15), 476-481 (2015)
Preliminary report on the osteogenic potential of a biodegradable copolymer of polyactide (PLA) and polyglycolide (PGA)
Hollinger JO
Journal of Biomedical Materials Research Part A, 17(1) (1983)
Diopside modified porous polyglycolide scaffolds with improved properties
Feng P, et al.
Royal Society of Chemistry Advances, 5, 54822-54829 (2015)