Skip to Content
Merck

471364

1-Dodecanethiol

≥98%

Synonym(s):

Dodecyl mercaptan, n-Dodecyl mercaptan, Lauryl mercaptan, Mercaptan C12, NDM

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

Linear Formula:
CH3(CH2)11SH
CAS Number:
Molecular Weight:
202.40
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-984-1
Beilstein/REAXYS Number:
969337
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

WNAHIZMDSQCWRP-UHFFFAOYSA-N

InChI

1S/C12H26S/c1-2-3-4-5-6-7-8-9-10-11-12-13/h13H,2-12H2,1H3

SMILES string

CCCCCCCCCCCCS

vapor density

7 (vs air)

assay

≥98%

Quality Level

bp

266-283 °C (lit.)

Looking for similar products? Visit Product Comparison Guide

General description

1-Dodecanethiol (DDT) is a premier alkanethiol for depositing highly ordered, hydrophobic Self-Assembled Monolayers (SAMs) on gold and noble metals. This ≥98% purity grade ensures crystalline-like molecular packing with minimal surface defects, critical for single-molecule electronics. As the gold standard for nanoparticle stabilization, its C12 chain offers the optimal balance between dense van der Waals packing and liquid-phase solubility, providing superior ease of handling compared to longer-chain analogs.

Application

As a versatile molecular bridge, DDT is essential for engineering intelligent interfaces and stimuli-responsive systems that enable precise interactions at the intersection of nanotechnology, biology, and electronics.


Nanoparticle Capping: Provides a robust hydrophobic shell for Gold, CdS, and PbS nanocrystals, preventing aggregation and enabling solvent-phase processing.


Steric Spacing: Acts as a critical "diluent" in mixed SAMs to precisely tune the lateral density of bulky bioreceptors (DNA/proteins), optimizing binding kinetics in biosensors.


Molecular Electronics: Serves as a foundational dielectric spacer in molecular junctions to study electron tunneling across individual organic molecules.


Quantum Dot Synthesis: Functions as a stable sulfur source for the solvothermal growth of magic-sized nanocrystals used in bio-imaging and optoelectronics.


Interface Protection: Forms a non-conductive, anti-corrosive barrier on copper and germanium surfaces for futuristic microelectronics and medical implants.

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1C - Skin Sens. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

262.4 °F - closed cup

flash_point_c

128 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

471364-BULK: + 471364-1L: + 471364-VAR: + 471364-500ML: + 471364-25ML: + 471364-100ML: + 471364-2L: + 471364-18L: + 471364-5L:

jan


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chemical synthesis and optical characterization of regular and magic-sized CdS quantum dot nanocrystals using 1-dodecanethiol.
Dickson R and Hu M
Journal of Materials Research, 30(7), 890-895 (2015)
Inhibition Effect of 3D Nanostructures on the Corrosion Resistance of 1-Dodecanethiol Self-Assembled Monolayers on Copper in Nacl Solution.
Shuai Hm et al.
Materials, 8(10), 11661-11679 (2018)
Functions of 1-Dodecanethiol in the Synthesis and Post-treatment of Copper Sulfide Nanoparticles Relevant to Their Photocatalytic Applications.
Lihui C and Guohua L
ACS Applied Nano Materials, 1(9), 4587?4593-4587?4593 (2018)
Pham Hong Phong et al.
Langmuir : the ACS journal of surfaces and colloids, 21(23), 10581-10586 (2005-11-03)
Ternary self-assembled monolayers (SAM) composed of 2-aminoethanethiol (AET), 2-mercaptoethanesulfonic acid (MES), and 1-dodecanethiol (DDeT) form two types of domains as if it were a two-component SAM: DDeT-rich hydrophobic domains and electrostatically stabilized hydrophilic domains composed of MES and AET on
Synthesis and characterization of PbS nanoparticles in an ionic liquid using single and dual source precursors.
Tshemese Z, et al.
Materials Science and Engineering, B, 227(7), 116-121 (2018)

Articles

自己組織化単分子層(SAM:self-assembled monolayer)は多様な用途があります。本稿では、金SAM系におけるアルキルチオラートの利点を比較しています。

酸化物や量子ドット、金属のナノ粒子合成に有用なソルボサーマル法について解説します。

自己組織化によって単一分子回路を作製する新しい方法と、分子と電極間の界面の化学的制御方法についてご紹介します。

HFAメタクリラートを含んだポジ型フォトレジストは、193nmドライリソグラフィを用いて製造したいくつかの世代のチップ生産に重要な役割を果たしています。

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service