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Merck

571245

Pyrene

sublimed grade, 99%

Synonym(s):

Benzo[def]phenanthrene

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About This Item

Empirical Formula (Hill Notation):
C16H10
CAS Number:
129-00-0
Molecular Weight:
202.25
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
24880620
EC Number:
204-927-3
Beilstein/REAXYS Number:
1307225
MDL number:
MFCD00004136
Assay:
99%

Key Documents

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InChI key

BBEAQIROQSPTKN-UHFFFAOYSA-N

InChI

1S/C16H10/c1-3-11-7-9-13-5-2-6-14-10-8-12(4-1)15(11)16(13)14/h1-10H

SMILES string

c1cc2ccc3cccc4ccc(c1)c2c34

grade

sublimed grade

assay

99%

Quality Level

100

Gene Information

human ... CYP1A2(1544)

fluorescence

λex 338 nm; λem 375 nm in DMSO

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Related Categories

pictograms

Environment
GHS09

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

435.2 °F

flash_point_c

224 °C

ppe

Eyeshields, Gloves

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - PBT - vPvB

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

571245-500MG: + 571245-BULK: + 571245-VAR: + 571245-1G:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
MKBX2204V
MKBQ9534V
MKBM4564V
MKBF8811V
MKBD4999

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Tatsuya Itoyama et al.
Marine pollution bulletin, 124(2), 792-797 (2017-03-06)
Pyrene, a member of the polycyclic aromatic hydrocarbons (PAHs), contributes to abnormality in the size of the brain and the swimming behavior of pufferfish (Takifugu niphobles) larvae. We hypothesized that the aryl hydrocarbon receptor (AHR) may mediate pyrene-induced toxic effects
Chufen Yang et al.
Materials science & engineering. C, Materials for biological applications, 84, 254-262 (2018-03-10)
To improve the drug release rate in well-controlled manner, a new pH-sensitive triblock amphiphilic copolymer methyl poly(ethylene glycol) ether-b-poly(β-amino esters)-b-poly lactic acid (MPEG-b-PBAE-b-PLA) and its self-assembled micelles were developed for anticancer drug delivery. The average molecular weight and molecular structure
Yeimy J Rodriguez et al.
Pharmaceutics, 12(3) (2020-02-29)
Amphotericin B (AmB) is a broad spectrum of antifungal drug used to treat antifungal diseases. However, due to the high toxicity of AmB, treated patients may suffer the risk of side effects, such as renal failure. Nanoencapsulation strategies have been
Hao Wang et al.
Acta biomaterialia, 72, 206-216 (2018-03-24)
While polysaccharide-based nanocarriers have been recognized for their crucial roles in tumor theranostics, the industrial-scale production of nanotherapeutics still remains a significant challenge. Most current approaches adopt a postpolymerization self-assembly strategy that follows a separate synthetic step and thus suffers
Pentti Somerharju
Chemistry and physics of lipids, 116(1-2), 57-74 (2002-07-03)
Pyrene is one of the most frequently used lipid-linked fluorophores. Its most characteristic features are a long excited state lifetime and (local) concentration-dependent formation of excimers. Pyrene is also hydrophobic and thus does not significantly distort the conformation of the
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