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Merck

674974

6-Mercaptohexanoic acid

90%

Synonym(s):

MHA

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About This Item

Empirical Formula (Hill Notation):
C6H12O2S
CAS Number:
17689-17-7
Molecular Weight:
148.22
NACRES:
NA.23
PubChem Substance ID:
24885247
UNSPSC Code:
12352103
MDL number:
MFCD08705278

Key Documents

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InChI

1S/C6H12O2S/c7-6(8)4-2-1-3-5-9/h9H,1-5H2,(H,7,8)

SMILES string

OC(=O)CCCCCS

InChI key

CMNQZZPAVNBESS-UHFFFAOYSA-N

assay

90%

refractive index

n20/D 1.4846

density

1.0715 g/mL at 25 °C

storage temp.

−20°C

Quality Level

100

Gene Information

rat ... Ace(24310)

Related Categories

General description

6-Mercaptohexanoic acid (MHA) forms a self-assembled monolayer (SAM) that is used to cap a variety of materials like gold nanoparticles (AuNPs) and indium phosphide quantum dots (InPQDs). It is majorly used in immobilizing the surface molecules, which enhance the physio-chemical and electrical properties.

Application

MHA can be used in the surface modification of InP quantum nanowires for their potential uage in fluorescent chemical sensors that monitor cyanide ions. MHA may also be covalently bonded with liposomes that can form a SAM on the surface of gold for use as an insect odorant receptor in biosensor based applications.
Used to prepare thiol-functionalized 1.5 nm gold nanoparticles via a ligand exchange process with triphenylphosphine-stabilized nanoparticles. This compound is used in self-assembly to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized with various amines and alcohols to introduce more complex end groups. Can also be used to control the rate of aggregation of gold colloidal nanoparticles using pH.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

674974-1G: + 674974-VAR: + 674974-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ0046
MKCM2881
MKCK4311
MKCJ7967
MKCG9522

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Renata Dobrucka et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 26(5), 643-650 (2018-07-12)
The interest in the biological synthesis of mono metal nanoparticles has been visible for years. As more attention is also given to the biological methods of synthesizing bimetallic nanoparticles, this work used the Agrimoniae herba extract in order to obtain
Raghavendra Ramalingam et al.
Nanomaterials (Basel, Switzerland), 9(3) (2019-03-23)
Electrospun fibers have emerged as promising materials in the field of biomedicine, due to their superior physical and cell supportive properties. In particular, electrospun mats are being developed for advanced wound dressing applications. Such applications require the firers to possess
An Ultrasensitive Electrochemical Impedance-Based Biosensor Using Insect Odorant Receptors to Detect Odorants
Khadka R, et al.
Biosensors And Bioelectronics, 183, 441-445 (2018)
Wenjuan Wei et al.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 50(6), 821-830 (2016-01-05)
Treatment of Acinetobacter baumannii infections is challenging owing to widespread multidrug-resistant A. baumannii (MDR-AB) and the lack of novel agents. Although recent data suggest that levofloxacin (LVX) may have unique activity against MDR-AB in combination with colistin (CST), further preclinical
J Lellouche et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(6), 711-716 (2018-10-07)
The rise in carbapenem resistance among Gram-negative bacteria has renewed interest in colistin. Recently, the EUCAST-CLSI Polymyxin Breakpoints Working Group declared that broth microdilution (BMD) is the only valid method for colistin susceptibility testing. BMD is not easily incorporated into
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Photopatterning Self-Assembled Monolayers

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