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705551

Hydrogen chloride solution

3 M in cyclopentyl methyl ether (CPME)

Synonym(s):

Hydrochloric acid in CPME

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About This Item

Empirical Formula (Hill Notation):
HCl
CAS Number:
7647-01-0
Molecular Weight:
36.46
NACRES:
NA.22
PubChem Substance ID:
329762569
UNSPSC Code:
12352301
MDL number:
MFCD00011324
Concentration:
2.85-3.30 M (silver nitrate titration), 3 M in cyclopentyl methyl ether (CPME)
Form:
liquid
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form

liquid

Quality Level

100

concentration

2.85-3.30 M (silver nitrate titration), 3 M in cyclopentyl methyl ether (CPME)

bp

106 °C

density

0.895 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

Cl

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

Application

Hydrogen chloride solution can be used in the Pinner synthesis of imidate hydrochlorides, which involves acid-catalyzed condensation of a nitrile and an alcohol under anhydrous conditions.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

flash_point_f

50.0 °F

flash_point_c

10 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

705551-100ML:4.548173297545E12

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The Chemistry of Imidates.
Roger R and Neilson D G
Chemical Reviews, 61(2), 179-211 (1961)
Marta Kolodziejczak et al.
ACS chemical neuroscience, 6(7), 1219-1230 (2015-04-11)
Maturation of functional neuronal circuits during central nervous system development relies on sophisticated mechanisms. First, axonal and dendritic growth should reach appropriate targets for correct synapse elaboration. Second, pruning and neuronal death are required to eliminate redundant or inappropriate neuronal
Douglas M McMillan et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(7), 1804-1812 (2015-01-30)
CYP2D metabolically activates codeine to morphine, which is required for codeine analgesia. Permeability across the blood-brain barrier, and active efflux, suggests that initial morphine in the brain after codeine is due to brain CYP2D metabolism. Human CYP2D is higher in
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