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Merck

751855

Hydrazine solution

1 M in acetonitrile

Synonym(s):

Hydrazine, Nitrogen hydride

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About This Item

Linear Formula:
NH2NH2
CAS Number:
Molecular Weight:
32.05
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
878137
Form:
liquid
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form

liquid

Quality Segment

concentration

1 M in acetonitrile

refractive index

n20/D 1.348

density

0.779 g/mL at 25 °C

functional group

hydrazine

SMILES string

NN

InChI

1S/H4N2/c1-2/h1-2H2

InChI key

OAKJQQAXSVQMHS-UHFFFAOYSA-N

General description

Hydrazine (N2H4) solution is a common reducing agent and a versatile reagent in organic synthesis. It can reduce a variety of functional groups like ketones, aldehydes, imines, nitro compounds, azides & nitrates to their corresponding amines. It also serves as a source of nitrogen in the synthesis of heterocyclic compounds, such as pyrazoles and pyrazolines.

Application

Hydrazine solution (in acetonitrile) can be used as a reducing source for the reduction of carbon-carbon multiple bonds in alkenes, alkynes, and α,β-unsaturated esters using metal-organic frameworks (MOFs) as heterogeneous catalysts. It is also used in the synthesis of polysubstituted 2-aminoimidazoles from 2-aminopyrimidines and α-bromocarbonyl compounds.


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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

41.0 °F

flash_point_c

5 °C


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

751855-800ML:4.548173336176E12 + 751855-100ML:4.548173336169E12

jan



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