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About This Item
Linear Formula:
H(C3H4O2)nOCH3
NACRES:
NA.23
UNSPSC Code:
12162002
form
solid
Quality Level
optical activity
[α]22/D -150°, c = 0.5% in chloroform
mol wt
average Mn 10,000
degradation timeframe
>3 years
transition temp
Tm 162-167 °C
PDI
≤1.1
storage temp.
2-8°C
General description
Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.
Application
Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
Features and Benefits
High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
非細胞性バイオプリンティングと細胞性バイオプリンティングの2種類の方法について、構造体に適した材料や製作方法を簡単に紹介します。
Aran教授は、多様な用途を可能にする慎重な機能化を通じたグラフェン系材料の設計について説明しています。
ポリラクチドおよびポリグリコリドを含む脂肪族ポリエステルは、医療用途に広く使用されている生分解性ポリマーです。
Effect of poly (ethylene glycol)-block- poly (L-lactide) on the poly [(R)-3-hydroxybutyrate]/poly (L-lactide) blends
Yoon, J. S., Lee, W. S., Kim, K. S., Chin, I. J., Kim, M. N., & Kim, C.
Eur. Polymer J., 36(2), 435-442 (2000)
Chemical synthesis of polylactide and its copolymers for medical applications
Bendix, D.
Polymer Degradation and Stability, 59(1), 129-135 (1998)
Synthesis and thermal properties of novel star-shaped poly (l-lactide)s with starburst PAMAM-OH dendrimer macroinitiator.
Zhao, Y. L., Cai, Q., Jiang, J., Shuai, X. T., Bei, J. Z., Chen, C. F., & Xi, F.
Polymer, 43(22), 5819-5825 (2002)