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Merck

81260

Poly(ethylene glycol)

greener alternative

average Mn 6,000, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
UNSPSC Code:
12352104
PubChem Substance ID:
24887720
NACRES:
NA.23
MDL number:
MFCD00081839

Key Documents

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Product Name

Poly(ethylene glycol), average Mn 6,000

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

form

flakes

mol wt

Mn 5,000-7,000, average Mn 6,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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pH

4.5-7.5

mp

60-63 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

Aligned

Quality Level

300

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General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

It has been used to modify therapeutic proteins and peptides to increase their solubility.
Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

81260-6X1KG: + 81260-VAR: + 81260-RSAMPLE: + 81260-5KG: + 81260-1KG: + 81260-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC1842
BCCC1843
BCCH0979
BCCH0980
BCCG5466

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Joo-Hyung Choi et al.
Veterinary microbiology, 236, 108374-108374 (2019-09-11)
Foot-and-mouth disease (FMD) is a highly contagious disease and causes economic damage at a national level. In particular, the type O FMD virus (FMDV) is a serotype that causes FMD outbreaks most frequently in the world. In recent years, Southeast
Ji Hyeon Hwang et al.
Journal of veterinary science, 20(3), e29-e29 (2019-06-05)
Vaccination is one of the most effective ways of controlling and preventing foot-and-mouth disease (FMD) outbreaks. The effective prevention of this disease requires the use of high-quality vaccines to meet the criteria that enable customers to use them simply. The
Su-Hwa You et al.
Veterinary microbiology, 234, 44-50 (2019-06-20)
Foot-and-mouth disease virus (FMDV) is the cause of an economically devastating disease in major cloven-hoofed livestock. Although type C foot-and-mouth disease (FMD) has not occurred anywhere worldwide since 2004, the antigen bank should be preserved in preparation for an unexpected
Fahad Zadjali et al.
International journal of molecular sciences, 21(5) (2020-03-07)
The tuberous sclerosis complex (Tsc) proteins regulate the conserved mTORC1 growth regulation pathway. We identified that loss of the Tsc2 gene in mouse inner medullary collecting duct (mIMCD) cells induced a greater than two-fold increase in extracellular vesicle (EV) production
Marc D Hein et al.
Applied microbiology and biotechnology, 105(1), 129-146 (2020-12-05)
The novel influenza A virus (IAV) defective interfering particle "OP7" inhibits IAV replication in a co-infection and was previously suggested as a promising antiviral agent. Here, we report a batch-mode cell culture-based production process for OP7. In the present study
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Articles

ポリエチレングリコール（PEG）：DDSと組織工学での活用・選択ガイド

ポリエチレングリコール（PEG）は、生物学的、化学的応用や医薬品開発に有用な化学的性質を有するエチレンオキシドと水との縮合ポリマーです。研究用途にPEGを使用する際に考慮すべき4つのポイントをご紹介します。

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